As "Luke Cage's" character in the new Primetime TV show "Evil" said, science is useful for studying repeatable things, but inadequate for the non-repeatable things in life. The latter includes certain areas of human relationships. No science can predict (other than in vague, non-specific generalities) how the uniqueness of two souls will have their individualities uniquely mix in 5, 10, or 20 years. How their quirks will affect each other. How their humour styles will integrate. How their creativity and originality will affect the creativity and originality of the other. How their free wills will respond to disappointment in the relationship. How their deepest passions will alchemically mix with each other (or fail to). You will never find a scientist who could comprehensively predict how their marriage with their partner would unfold in these areas (as well as some others) after a year. The soul transcends the "closed system of cause-and-effect in time and space". It receives influence, and influences, the spiritual realm in ways that transcend the ticking of time and the sensing of space. You take the originality of two souls and unify them together, and you'll get a drama full of unpredictable, non-repeatable transformations in relationships.

And supernatural life-giving miracles are relational acts from a relational God. They are not impersonal mechanisms.

(By the way, the show Evil is sooo good.)